Engineered from the finest genes and trained to be a secret courier in a future world, Friday operates over a near-future Earth, where chaos reigns. North America has become Balkanized into dozens of independent states, sharing only a bizarrely vulgarized culture.  Now, Friday finds herself on shuttlecock assignment at the seemingly whimsical behest of her secret employer, known to her only as “Boss”. Traveling from one to another of the new states of America's disunion, she is confronted with a series of professional as well as personal crises that put her to the test.